Active: Front Immunol Clear all

GWAS 2024-11-15

A genome-wide cross-trait analysis identifying shared genetic basis and causal relationships between Hunner-type interstitial cystitis and autoimmune diseases in East Asian populations.

Lyu X, Peng L et al.

Front Immunol

Purpose: Epidemiological studies have demonstrated the clinical link between Hunner interstitial cys...

Hunner-type interstitial cystitis or atopic dermatitis (MTAG)

190904

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-15

Shared genetic architecture between COVID-19 and irritable bowel syndrome: a large-scale genome-wide cross-trait analysis.

Liu X, Li D et al.

Front Immunol

It has been reported that COVID-19 patients have an increased risk of developing IBS; however, the u...

Irritable bowel syndrome or COVID-19 susceptibility / hospitalization (MTAG)

5519491

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-04

Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of Staphylococcus aureus.

Weiss S, Holtfreter S et al.

Front Immunol

Life-threatening toxic shock syndrome is often caused by the superantigen toxic shock syndrome toxin...

Anti-TSST-1 total IgG levels

969

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-16

A shared genetic contribution to osteoarthritis and COVID-19 outcomes: a large-scale genome-wide cross-trait analysis.

Huang YX, Tian T et al.

Front Immunol

Patients with osteoarthritis (OA) are exposed to an increased risk of adverse outcomes of COVID-19, ...

Critical COVID-19 or osteoarthritis (MTAG)

1703212

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-12

Identifying shared genetic loci and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies.

Wen YP, Yu ZG

Front Immunol

Introduction: Substantial links between autoimmune diseases have been shown by an increasing number ...

Rheumatoid arthritis or multiple sclerosis

453670

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-14

Integration of Candida albicans-induced single-cell gene expression data and secretory protein concentrations reveal genetic regulators of inflammation.

Boahen CK, Oelen R et al.

Front Immunol

Both gene expression and protein concentrations are regulated by genetic variants. Exploring the reg...

CCL20 levels

445

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-01

Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator.

Cardinale CJ, Chang X et al.

Front Immunol

Introduction: Type 1 diabetes, a disorder caused by autoimmune destruction of pancreatic insulin-pro...

Type 1 diabetes (age at diagnosis)

Replicated

4507

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-14

Pilot genome-wide association study of antibody response to inactivated SARS-CoV-2 vaccines.

Li P, Shi D et al.

Front Immunol

Vaccines are a key weapon against the COVID-19 pandemic caused by SARS-CoV-2. However, there are int...

IgG antibody levels in response to SARS-CoV-2 vaccination

168

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-03

Genome-wide association study of SNP- and gene-based approaches to identify susceptibility candidates for lupus nephritis in the Han Chinese population.

Song K, Zheng X et al.

Front Immunol

Lupus nephritis (LN) is one of the most common and serious complications of systemic lupus erythaema...

Lupus nephritis in systemic lupus erythematosus

Replicated

1404

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-22

Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.

Höglund J, Hadizadeh F et al.

Front Immunol

Eosinophils play important roles in the release of cytokine mediators in response to inflammation. M...

Eosinophil count

365954

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-25

Impact of Human Genetic Variation on C-Reactive Protein Concentrations and Acute Appendicitis.

Ricaño-Ponce I, Peeters T et al.

Front Immunol

Acute appendicitis is one of the most common abdominal emergencies worldwide. Both environmental and...

Complicated vs uncomplicated appendicitis

285

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-21

Causal Association and Shared Genetics Between Asthma and COVID-19.

Baranova A, Cao H et al.

Front Immunol

Objectives: Recent studies suggest that asthma may have a protective effect on COVID-19.We aimed to ...

Asthma or COVID-19 (pleiotropy)

1444839

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide cross-trait analysis identifying shared genetic basis and causal relationships between Hunner-type interstitial cystitis and autoimmune diseases in East Asian populations.

Lyu X, Peng L et al.

Front Immunol

Hunner-type interstitial cystitis or atopic dermatitis (MTAG)

2024-11-15

Shared genetic architecture between COVID-19 and irritable bowel syndrome: a large-scale genome-wide cross-trait analysis.

Liu X, Li D et al.

Front Immunol

Irritable bowel syndrome or COVID-19 susceptibility / hospitalization (MTAG)

2024-11-15

Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of Staphylococcus aureus.

Weiss S, Holtfreter S et al.

Front Immunol

Anti-TSST-1 total IgG levels

2023-09-04

A shared genetic contribution to osteoarthritis and COVID-19 outcomes: a large-scale genome-wide cross-trait analysis.

Huang YX, Tian T et al.

Front Immunol

Critical COVID-19 or osteoarthritis (MTAG)

2023-06-16

Identifying shared genetic loci and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies.

Wen YP, Yu ZG

Front Immunol

Rheumatoid arthritis or multiple sclerosis

2023-06-12

Integration of Candida albicans-induced single-cell gene expression data and secretory protein concentrations reveal genetic regulators of inflammation.

Boahen CK, Oelen R et al.

Front Immunol

CCL20 levels

2023-02-14

Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator.

Cardinale CJ, Chang X et al.

Front Immunol

Type 1 diabetes (age at diagnosis)

2023-02-01

Pilot genome-wide association study of antibody response to inactivated SARS-CoV-2 vaccines.

Li P, Shi D et al.

Front Immunol

IgG antibody levels in response to SARS-CoV-2 vaccination

2022-11-14

Genome-wide association study of SNP- and gene-based approaches to identify susceptibility candidates for lupus nephritis in the Han Chinese population.

Song K, Zheng X et al.

Front Immunol

Lupus nephritis in systemic lupus erythematosus

2022-10-03

Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.

Höglund J, Hadizadeh F et al.

Front Immunol

Eosinophil count

2022-07-22

Impact of Human Genetic Variation on C-Reactive Protein Concentrations and Acute Appendicitis.

Ricaño-Ponce I, Peeters T et al.

Front Immunol

Complicated vs uncomplicated appendicitis

2022-05-25

Causal Association and Shared Genetics Between Asthma and COVID-19.

Baranova A, Cao H et al.

Front Immunol

Asthma or COVID-19 (pleiotropy)

2022-03-21

Health & Traits Publications

A genome-wide cross-trait analysis identifying shared genetic basis and causal relationships between Hunner-type interstitial cystitis and autoimmune diseases in East Asian populations.

Shared genetic architecture between COVID-19 and irritable bowel syndrome: a large-scale genome-wide cross-trait analysis.

Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of <i>Staphylococcus aureus</i>.

A shared genetic contribution to osteoarthritis and COVID-19 outcomes: a large-scale genome-wide cross-trait analysis.

Identifying shared genetic loci and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies.

Integration of <i>Candida albicans</i>-induced single-cell gene expression data and secretory protein concentrations reveal genetic regulators of inflammation.

Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator.

Pilot genome-wide association study of antibody response to inactivated SARS-CoV-2 vaccines.

Genome-wide association study of SNP- and gene-based approaches to identify susceptibility candidates for lupus nephritis in the Han Chinese population.

Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.

Impact of Human Genetic Variation on C-Reactive Protein Concentrations and Acute Appendicitis.

Causal Association and Shared Genetics Between Asthma and COVID-19.