Active: Sarcoidosis Clear all

GWAS 2025-12-29

Genome-wide association for sarcoidosis identifies novel risk loci and genetic heritability in African and European ancestries: a meta-analysis from the Finngen, Million Veteran Program, UK Biobank, and Biobank Japan datasets.

Ricci A

Orphanet J Rare Dis

Sarcoidosis

1369285

Participants

N/A

Studies

Details PubMed

GWAS 2025-03-12

GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis.

Yuan S, Chen J et al.

Nat Commun

Sarcoidosis is a complex inflammatory disease with a strong genetic component. Here, we perform a ge...

Sarcoidosis

1536622

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-03

Genome-wide association study identifies multiple HLA loci for sarcoidosis susceptibility.

Liao SY, Jacobson S et al.

Hum Mol Genet

Sarcoidosis is a complex systemic disease. Our study aimed to (1) identify novel alleles associated ...

Sarcoidosis

2599

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-21

Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis.

Meguro A, Ishihara M et al.

Commun Biol

Sarcoidosis is a genetically complex systemic inflammatory disease that affects multiple organs. We ...

Sarcoidosis

Replicated

3989

Participants

N/A

Studies

Details PubMed

GWAS 2020-03-06

Genome-Wide Association Study of Ocular Sarcoidosis Confirms HLA Associations and Implicates Barrier Function and Autoimmunity in African Americans.

Garman L, Pezant N et al.

Ocul Immunol Inflamm

Purpose: Identify genes associated with ocular sarcoidosis (OS).Methods: We genotyped 1.1 million ge...

Ocular sarcoidosis

1811

Participants

N/A

Studies

Details PubMed

GWAS 2019-12-09

A Gene-Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis.

Rivera NV, Patasova K et al.

Sci Rep

The influence and effect of cigarette smoking in sarcoidosis is unclear. Here, we evaluated gene-env...

Sarcoidosis (non-Lofgren's syndrome) (smoking status interaction)

3421

Participants

N/A

Studies

Details PubMed

GWAS 2016-05-01

High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.

Rivera NV, Ronninger M et al.

Am J Respir Crit Care Med

Rationale: Sarcoidosis is a multisystem disease of unknown cause. Löfgren's syndrome (LS) is a chara...

Sarcoidosis (non-Lofgren's syndrome)

Replicated

9914

Participants

N/A

Studies

Details PubMed

GWAS 2015-09-15

Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk.

Fischer A, Ellinghaus D et al.

Am J Respir Crit Care Med

Rationale: Genetic variation plays a significant role in the etiology of sarcoidosis. However, only ...

Sarcoidosis

Replicated

16715

Participants

N/A

Studies

Details PubMed

GWAS 2012-08-30

Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis.

Hofmann S, Fischer A et al.

Eur Respir J

Sarcoidosis is a systemic inflammatory disease of unknown aetiology, influenced by genetic and envir...

Sarcoidosis

Replicated

9275

Participants

N/A

Studies

Details PubMed

GWAS 2012-08-27

Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.

Adrianto I, Lin CP et al.

PLoS One

Sarcoidosis is a systemic inflammatory disease characterized by the formation of granulomas in affec...

Sarcoidosis

2918

Participants

N/A

Studies

Details PubMed

GWAS 2012-07-26

A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.

Fischer A, Schmid B et al.

Am J Respir Crit Care Med

Rationale: Sarcoidosis is a complex inflammatory disease with a heterogeneous clinical picture. Amon...

Sarcoidosis

Replicated

8878

Participants

N/A

Studies

Details PubMed

GWAS 2011-05-03

A genome-wide association study reveals evidence of association with sarcoidosis at 6p12.1.

Hofmann S, Fischer A et al.

Eur Respir J

Sarcoidosis is a complex systemic inflammatory disease of unknown aetiology that is influenced by a ...

Sarcoidosis

Replicated

4138

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association for sarcoidosis identifies novel risk loci and genetic heritability in African and European ancestries: a meta-analysis from the Finngen, Million Veteran Program, UK Biobank, and Biobank Japan datasets.

Ricci A

Orphanet J Rare Dis

Sarcoidosis

2025-12-29

GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis.

Yuan S, Chen J et al.

Nat Commun

Sarcoidosis

2025-03-12

Genome-wide association study identifies multiple HLA loci for sarcoidosis susceptibility.

Liao SY, Jacobson S et al.

Hum Mol Genet

Sarcoidosis

2023-07-03

Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis.

Meguro A, Ishihara M et al.

Commun Biol

Sarcoidosis

2020-08-21

Genome-Wide Association Study of Ocular Sarcoidosis Confirms HLA Associations and Implicates Barrier Function and Autoimmunity in African Americans.

Garman L, Pezant N et al.

Ocul Immunol Inflamm

Ocular sarcoidosis

2020-03-06

A Gene-Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis.

Rivera NV, Patasova K et al.

Sci Rep

Sarcoidosis (non-Lofgren's syndrome) (smoking status interaction)

2019-12-09

High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.

Rivera NV, Ronninger M et al.

Am J Respir Crit Care Med

Sarcoidosis (non-Lofgren's syndrome)

2016-05-01

Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk.

Fischer A, Ellinghaus D et al.

Am J Respir Crit Care Med

Sarcoidosis

2015-09-15

Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis.

Hofmann S, Fischer A et al.

Eur Respir J

Sarcoidosis

2012-08-30

Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.

Adrianto I, Lin CP et al.

PLoS One

Sarcoidosis

2012-08-27

A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.

Fischer A, Schmid B et al.

Am J Respir Crit Care Med

Sarcoidosis

2012-07-26

A genome-wide association study reveals evidence of association with sarcoidosis at 6p12.1.

Hofmann S, Fischer A et al.

Eur Respir J

Sarcoidosis

2011-05-03