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GWAS Study

Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk.

Fischer A, Ellinghaus D, Nutsua M et al.

26051272 PubMed ID
GWAS Study Type
16715 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FA
Fischer A
ED
Ellinghaus D
NM
Nutsua M
HS
Hofmann S
MC
Montgomery CG
IM
Iannuzzi MC
RB
Rybicki BA
PM
Petrek M
MF
Mrazek F
PS
Pabst S
GC
Grohé C
GJ
Grunewald J
RM
Ronninger M
EA
Eklund A
PL
Padyukov L
MV
Mihailovic-Vucinic V
JD
Jovanovic D
SM
Sterclova M
HJ
Homolka J
NM
Nöthen MM
HS
Herms S
GC
Gieger C
SK
Strauch K
WJ
Winkelmann J
BB
Boehm BO
BS
Brand S
BC
Büning C
SM
Schürmann M
EE
Ellinghaus E
BH
Baurecht H
LW
Lieb W
NA
Nebel A
MJ
Müller-Quernheim J
FA
Franke A
SS
Schreiber S
Chapter II

Abstract

Summary of the research findings

Rationale: Genetic variation plays a significant role in the etiology of sarcoidosis. However, only a small fraction of its heritability has been explained so far.

1,726 European ancestry cases, 5,482 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

16715
Total Participants
GWAS
Study Type
Yes
Replicated
1,912 European ancestry cases, 5,938 European ancestry controls, 781 African American cases, 876 African American controls
Replication Participants
African American or Afro-Caribbean, European
Ancestry
U.S., Germany, Czech Republic, Sweden
Recruitment Country
Chapter IV

AI-Generated Summary

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