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GWAS Study

A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.

Fischer A, Schmid B, Ellinghaus D et al.

22837380 PubMed ID
GWAS Study Type
8878 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FA
Fischer A
SB
Schmid B
ED
Ellinghaus D
NM
Nothnagel M
GK
Gaede KI
SM
Schürmann M
LS
Lipinski S
RP
Rosenstiel P
ZG
Zissel G
HK
Höhne K
PM
Petrek M
KV
Kolek V
PS
Pabst S
GC
Grohé C
GJ
Grunewald J
RM
Ronninger M
EA
Eklund A
PL
Padyukov L
GC
Gieger C
WH
Wichmann HE
NA
Nebel A
FA
Franke A
MJ
Müller-Quernheim J
HS
Hofmann S
SS
Schreiber S
Chapter II

Abstract

Summary of the research findings

Rationale: Sarcoidosis is a complex inflammatory disease with a heterogeneous clinical picture. Among others, an acute and chronic clinical course can be distinguished, for which specific genetic risk factors are known.

564 European ancestry cases, 1,575 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

8878
Total Participants
GWAS
Study Type
Yes
Replicated
3,080 European ancestry cases, 3,659 European ancestry controls
Replication Participants
European
Ancestry
Germany, Sweden, Czech Republic
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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