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GWAS 2025-09-30

Genome-wide association study of susceptibility to acute respiratory distress syndrome.

Guillen-Guio B, Suarez-Pajes E et al.

EBioMedicine

Acute respiratory distress syndrome (ARDS) is a severe inflammatory process of the lung, often due t...

Acute respiratory distress syndrome

Replicated

6943

Participants

N/A

Studies

Details PubMed

GWAS 2025-07-08

GWAS meta-analysis identifies five susceptibility loci for endometrial cancer.

Ramachandran D, Wang X et al.

EBioMedicine

Endometrial cancer is the most common gynaecological cancer in high-income countries. In addition to...

Endometrial cancer

Replicated

309002

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-04

Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease.

Kurniansyah N, Strausz SJ et al.

EBioMedicine

Obstructive sleep apnoea (OSA) is a common chronic condition, with obesity its strongest risk factor...

Obstructive sleep apnea

182017

Participants

N/A

Studies

Details PubMed

GWAS 2025-01-02

Genetic factors shaping the plasma lipidome and the relations to cardiometabolic risk in children and adolescents.

Huang Y, Stinson SE et al.

EBioMedicine

Lipid species are emerging as biomarkers for cardiometabolic risk in both adults and children. The g...

Lysophosphatidylcholine (22:4/0:0) levels

1149

Participants

N/A

Studies

Details PubMed

GWAS 2024-07-05

Polygenic inheritance and its interplay with smoking history in predicting lung cancer diagnosis: a French-Canadian case-control cohort.

Boumtje V, Manikpurage HD et al.

EBioMedicine

The most near-term clinical application of genome-wide association studies in lung cancer is a polyg...

Lung cancer

24012

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-14

Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer.

Papadimitriou N, Kim A et al.

EBioMedicine

Consumption of fibre, fruits and vegetables have been linked with lower colorectal cancer (CRC) risk...

Colorectal cancer x fruit intake interaction (3df)

69599

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-06

Genome-wide association study identifies genetic regulation of oestrone concentrations and association with endometrial cancer risk in postmenopausal women.

Yu C, Bakshi A et al.

EBioMedicine

Oestrone, predominantly made in fat, is the main circulating oestrogen and important for target tiss...

Oestrone levels

4951

Participants

N/A

Studies

Details PubMed

GWAS 2023-08-22

The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses.

Faber BG, Frysz M et al.

EBioMedicine

Hip minimum joint space width (mJSW) provides a proxy for cartilage thickness. This study aimed to c...

Hip minimal joint space width

50745

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-18

Dissecting the genetic heterogeneity of gastric cancer.

Hess T, Maj C et al.

EBioMedicine

Gastric cancer (GC) is clinically heterogenous according to location (cardia/non-cardia) and histopa...

Gastric cancer

16814

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-04

A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration.

Clark R, Lee SS et al.

EBioMedicine

High myopia (HM), defined as a spherical equivalent refractive error (SER) ≤ -6.00 diopters (D), is ...

Spherical equivalent refractive error averaged between the 2 eyes (MTAG)

468769

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-27

Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sex.

Sofer T, Kurniansyah N et al.

EBioMedicine

Genome-wide association studies (GWAS) for obstructive sleep apnoea (OSA) are limited due to the und...

Obstructive sleep apnea

916696

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-13

Genome-wide association meta-analysis of 88,250 individuals highlights pleiotropic mechanisms of five ocular diseases in UK Biobank.

Xue Z, Yuan J et al.

EBioMedicine

Ocular diseases may exhibit common clinical symptoms and epidemiological comorbidity. However, the e...

Age-related macular degeneration

66387

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association study of susceptibility to acute respiratory distress syndrome.

Guillen-Guio B, Suarez-Pajes E et al.

EBioMedicine

Acute respiratory distress syndrome

2025-09-30

GWAS meta-analysis identifies five susceptibility loci for endometrial cancer.

Ramachandran D, Wang X et al.

EBioMedicine

Endometrial cancer

2025-07-08

Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease.

Kurniansyah N, Strausz SJ et al.

EBioMedicine

Obstructive sleep apnea

2025-06-04

Genetic factors shaping the plasma lipidome and the relations to cardiometabolic risk in children and adolescents.

Huang Y, Stinson SE et al.

EBioMedicine

Lysophosphatidylcholine (22:4/0:0) levels

2025-01-02

Polygenic inheritance and its interplay with smoking history in predicting lung cancer diagnosis: a French-Canadian case-control cohort.

Boumtje V, Manikpurage HD et al.

EBioMedicine

Lung cancer

2024-07-05

Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer.

Papadimitriou N, Kim A et al.

EBioMedicine

Colorectal cancer x fruit intake interaction (3df)

2024-05-14

Genome-wide association study identifies genetic regulation of oestrone concentrations and association with endometrial cancer risk in postmenopausal women.

Yu C, Bakshi A et al.

EBioMedicine

Oestrone levels

2024-02-06

The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses.

Faber BG, Frysz M et al.

EBioMedicine

Hip minimal joint space width

2023-08-22

Dissecting the genetic heterogeneity of gastric cancer.

Hess T, Maj C et al.

EBioMedicine

Gastric cancer

2023-05-18

A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration.

Clark R, Lee SS et al.

EBioMedicine

Spherical equivalent refractive error averaged between the 2 eyes (MTAG)

2023-04-04

Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sex.

Sofer T, Kurniansyah N et al.

EBioMedicine

Obstructive sleep apnea

2023-03-27

Genome-wide association meta-analysis of 88,250 individuals highlights pleiotropic mechanisms of five ocular diseases in UK Biobank.

Xue Z, Yuan J et al.

EBioMedicine

Age-related macular degeneration

2022-07-13