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GWAS Study

GWAS meta-analysis identifies five susceptibility loci for endometrial cancer.

Ramachandran D, Wang X, Laisk T et al.

40633141 PubMed ID
GWAS Study Type
309002 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RD
Ramachandran D
WX
Wang X
LT
Laisk T
ZY
Zheng Y
IN
Ingold N
CD
Canson DM
KP
Kho PF
NB
Naumann BJ
CC
Chapman CJ
BK
Bousset K
KA
Krause AV
SP
Schürmann P
WB
Wieland B
HP
Hanel P
HF
Hülse F
HN
Häfner N
RI
Runnebaum I
DN
Dubrowinskaja N
TN
Turmanov N
YT
Yugay T
YZ
Yessimsiitova ZB
AF
Amant F
AD
Annibali D
BM
Beckmann MW
BC
Bodelon C
BD
Buchanan DD
CC
Chen C
CM
Clarke MA
CL
Cook LS
DV
De Vivo I
DW
De Wispelaere W
DM
Du M
ED
Easton DF
EJ
Emons J
FP
Fasching PA
FC
Friedenreich CM
GG
Gallagher G
GG
Giles GG
GE
Goode EL
HH
Harris HR
HD
Hunter DJ
KD
Kolin DL
KP
Kraft P
LJ
Lacey JV
LD
Lambrechts D
LL
Lu L
MG
Mutter GL
NJ
Naduparambil J
OK
O'Connell K
PA
Patel AV
PP
Pharoah PDP
RT
Rebbeck TR
RF
Ricceri F
RH
Risch HA
RM
Ruebner M
SC
Sacerdote C
SR
Scott RJ
SV
Setiawan VW
SX
Shu XO
SM
Southey MC
TE
Tham E
TI
Tomlinson I
TC
Turman C
WN
Wentzensen N
XW
Xu W
YH
Yu H
ZW
Zheng W
SA
Spurdle AB
YY
Yarden Y
MR
Mägi R
HP
Hillemanns P
GD
Glubb DM
DT
Dörk T
OT
O'Mara TA
Chapter II

Abstract

Summary of the research findings

Endometrial cancer is the most common gynaecological cancer in high-income countries. In addition to environmental risk factors, genetic predisposition contributes towards endometrial cancer development but is still incompletely defined.

1,200 European ancestry female cases, 60,614 European ancestry female controls, 16,078 East Asian ancestry female cases, 228,566 East Asian ancestry female controls

Chapter III

Study Statistics

Key metrics and study information

309002
Total Participants
GWAS
Study Type
Yes
Replicated
718 European ancestry female cases, 1,206 European ancestry female controls, 100 Central Asian ancestry female cases, 489 Central Asian ancestry female controls, 22 Asian ancestry female cases, 9 Asian ancestry female controls
Replication Participants
European, East Asian, Central Asian, Asian unspecified
Ancestry
U.S., Finland, U.K., Australia, Germany, Estonia, Japan, Kazakhstan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.