Active: Rheumatology (Oxford) Clear all

GWAS 2024-02-05

Revealing Novel Genomic Insights and Therapeutic Targets for Juvenile Idiopathic Arthritis through Omics.

Fan J, Li X et al.

Rheumatology (Oxford)

The genetic architecture of JIA remains only partially comprehended. There is a clear imperative for...

Juvenile idiopathic arthritis

22996

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-16

Genome-wide investigation of persistence to treatment with methotrexate in early rheumatoid arthritis.

Sysojev AÖ, Saevarsdottir S et al.

Rheumatology (Oxford)

Objectives: To investigate the influence of genetic factors on persistence with treatment of early R...

Persistence with methotrexate treatment at one year in early rheumatoid arthritis

3260

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-18

Genetics of Osteonecrosis in Children and Adults with Systemic Lupus Erythematosus.

Webber D, Cao J et al.

Rheumatology (Oxford)

Objectives: Genetics plays an important role in SLE risk, as well as osteonecrosis (ON), a significa...

Osteonecrosis (time to event) in systemic lupus erythematosus

940

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-27

Genetic contributions to female gout and hyperuricemia using genome-wide association study and polygenic risk score analyses.

Lin CY, Chang YS et al.

Rheumatology (Oxford)

Objectives: To identify genetic variants and polygenic risk score (PRS) relating to female gout and ...

Gout (age >=50)

19581

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-16

Identification of a shared genetic risk locus for Kawasaki disease and IgA vasculitis by a cross-phenotype meta-analysis.

Carmona EG, García-Giménez JA et al.

Rheumatology (Oxford)

Objectives: Combining of genomic data of different pathologies as a single phenotype has emerged as ...

Kawasaki disease or immunoglobulin A vasculitis (pleiotropy)

Replicated

12451

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-25

Genome-wide association study on Northern Chinese identifies KLF2, DOT1L and STAB2 associated with systemic lupus erythematosus.

Song Q, Lei Y et al.

Rheumatology (Oxford)

Objectives: To identify novel genetic loci associated with systemic lupus erythematosus (SLE) and to...

Systemic lupus erythematosus

1506

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-17

An association between chronic widespread pain and the gut microbiome.

Freidin MB, Stalteri MA et al.

Rheumatology (Oxford)

Objectives: Chronic widespread musculoskeletal pain (CWP) is a characteristic symptom of fibromyalgi...

Coprococcus comes

3521

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-21

Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study.

González-Serna D, López-Isac E et al.

Rheumatology (Oxford)

Objectives: SSc is an autoimmune disease characterized by alteration of the immune response, vasculo...

Systemic sclerosis

2107

Participants

N/A

Studies

Details PubMed

GWAS 2015-08-13

An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis.

Jiang X, Källberg H et al.

Rheumatology (Oxford)

Objective: To investigate the gene-environment interaction between smoking and single nucleotide pol...

ACPA-negative rheumatoid arthritis (smoking interaction)

Replicated

2573

Participants

N/A

Studies

Details PubMed

GWAS 2011-12-16

Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences.

Lai HM, Chen CJ et al.

Rheumatology (Oxford)

Objective: To explore the causal relationship between gout and Type 2 diabetes based on genetic evid...

Gout

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Revealing Novel Genomic Insights and Therapeutic Targets for Juvenile Idiopathic Arthritis through Omics.

Fan J, Li X et al.

Rheumatology (Oxford)

Juvenile idiopathic arthritis

2024-02-05

Genome-wide investigation of persistence to treatment with methotrexate in early rheumatoid arthritis.

Sysojev AÖ, Saevarsdottir S et al.

Rheumatology (Oxford)

Persistence with methotrexate treatment at one year in early rheumatoid arthritis

2023-06-16

Genetics of Osteonecrosis in Children and Adults with Systemic Lupus Erythematosus.

Webber D, Cao J et al.

Rheumatology (Oxford)

Osteonecrosis (time to event) in systemic lupus erythematosus

2023-01-18

Genetic contributions to female gout and hyperuricemia using genome-wide association study and polygenic risk score analyses.

Lin CY, Chang YS et al.

Rheumatology (Oxford)

Gout (age >=50)

2022-06-27

Identification of a shared genetic risk locus for Kawasaki disease and IgA vasculitis by a cross-phenotype meta-analysis.

Carmona EG, García-Giménez JA et al.

Rheumatology (Oxford)

Kawasaki disease or immunoglobulin A vasculitis (pleiotropy)

2021-05-16

Genome-wide association study on Northern Chinese identifies KLF2, DOT1L and STAB2 associated with systemic lupus erythematosus.

Song Q, Lei Y et al.

Rheumatology (Oxford)

Systemic lupus erythematosus

2021-01-25

An association between chronic widespread pain and the gut microbiome.

Freidin MB, Stalteri MA et al.

Rheumatology (Oxford)

Coprococcus comes

2020-12-17

Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study.

González-Serna D, López-Isac E et al.

Rheumatology (Oxford)

Systemic sclerosis

2018-09-21

An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis.

Jiang X, Källberg H et al.

Rheumatology (Oxford)

ACPA-negative rheumatoid arthritis (smoking interaction)

2015-08-13

Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences.

Lai HM, Chen CJ et al.

Rheumatology (Oxford)

Gout

2011-12-16