Fourteen ancient genomes from sites in western Anatolia (Stratonikeia, Lagina, Stratonikeia-West Church, Iznik basilica, and Ilıpınar) provide a first-order genetic portrait of Byzantine-era communities in this region. Maternal lineages are dominated by western Eurasian haplogroups: H (3 counts including H5f), U (3), X (2), and J (1). These mtDNA profiles are consistent with broader Mediterranean and Anatolian maternal ancestry observed in a number of ancient and modern datasets.
Y-chromosome haplogroups were not consistently reported across these 14 samples, so paternal-line patterns remain less certain for this dataset. With a modest sample size, interpretations must be cautious: the 14 genomes offer valuable signals but cannot capture the full demographic complexity of Byzantine Anatolia. Archaeogenetic analyses indicate a mixture of local Anatolian ancestry with continued gene flow from Mediterranean and, at times, Balkan or eastern influences—reflecting trade, migration, and imperial connections.
Importantly, the mtDNA composition suggests continuity of local maternal lines through centuries of cultural change rather than wholesale population replacement. Still, finer-scale admixture modeling and larger sample counts would be needed to resolve contributions from specific source populations (e.g., Anatolian Neolithic descendant groups, Aegean populations, or post-Roman migrants).