Active: JAMA Neurol Clear all

GWAS 2024-09-09

Role of the X Chromosome in Alzheimer Disease Genetics.

Belloy ME, Le Guen Y et al.

JAMA Neurol

Importance: The X chromosome has remained enigmatic in Alzheimer disease (AD), yet it makes up 5% of...

Alzheimer's disease

1152284

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-04

Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study and Meta-analysis.

Liao C, Castonguay CE et al.

JAMA Neurol

Importance: Essential tremor (ET) is one of the most common movement disorders, affecting 5% of the ...

Essential tremor

483054

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-19

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.

Kunkle BW, Schmidt M et al.

JAMA Neurol

Importance: Compared with non-Hispanic White individuals, African American individuals from the same...

Alzheimer's disease

8006

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-22

Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.

Raghavan NS, Dumitrescu L et al.

JAMA Neurol

Importance: Genetic studies of Alzheimer disease have focused on the clinical or pathologic diagnosi...

Brain amyloid deposition (PET imaging)

4314

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-20

Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study.

Foo JN, Chew EGY et al.

JAMA Neurol

Importance: Large-scale genome-wide association studies in the European population have identified 9...

Parkinson's disease

Replicated

1961445

Participants

N/A

Studies

Details PubMed

GWAS 2016-05-31

Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis.

Fogh I, Lin K et al.

JAMA Neurol

Importance: Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset neurodegenerative disor...

Survival in sporadic amyotrophic lateral sclerosis

4256

Participants

N/A

Studies

Details PubMed

GWAS 2015-04-01

A genome-wide association study of myasthenia gravis.

Renton AE, Pliner HA et al.

JAMA Neurol

Importance: Myasthenia gravis is a chronic, autoimmune, neuromuscular disease characterized by fluct...

Myasthenia gravis

Replicated

3839

Participants

N/A

Studies

Details PubMed

GWAS 2013-09-01

Genetic susceptibility for Alzheimer disease neuritic plaque pathology.

Shulman JM, Chen K et al.

JAMA Neurol

Importance: While numerous genetic susceptibility loci have been identified for clinical Alzheimer d...

Alzheimer's disease (neuritic plaque pathology)

Replicated

765

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Role of the X Chromosome in Alzheimer Disease Genetics.

Belloy ME, Le Guen Y et al.

JAMA Neurol

Alzheimer's disease

2024-09-09

Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study and Meta-analysis.

Liao C, Castonguay CE et al.

JAMA Neurol

Essential tremor

2022-01-04

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.

Kunkle BW, Schmidt M et al.

JAMA Neurol

Alzheimer's disease

2020-10-19

Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.

Raghavan NS, Dumitrescu L et al.

JAMA Neurol

Brain amyloid deposition (PET imaging)

2020-06-22

Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study.

Foo JN, Chew EGY et al.

JAMA Neurol

Parkinson's disease

2020-04-20

Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis.

Fogh I, Lin K et al.

JAMA Neurol

Survival in sporadic amyotrophic lateral sclerosis

2016-05-31

A genome-wide association study of myasthenia gravis.

Renton AE, Pliner HA et al.

JAMA Neurol

Myasthenia gravis

2015-04-01

Genetic susceptibility for Alzheimer disease neuritic plaque pathology.

Shulman JM, Chen K et al.

JAMA Neurol

Alzheimer's disease (neuritic plaque pathology)

2013-09-01