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GWAS Study

Genetic susceptibility for Alzheimer disease neuritic plaque pathology.

Shulman JM, Chen K, Keenan BT et al.

23836404 PubMed ID
GWAS Study Type
765 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SJ
Shulman JM
CK
Chen K
KB
Keenan BT
CL
Chibnik LB
FA
Fleisher A
TP
Thiyyagura P
RA
Roontiva A
MC
McCabe C
PN
Patsopoulos NA
CJ
Corneveaux JJ
YL
Yu L
HM
Huentelman MJ
ED
Evans DA
SJ
Schneider JA
RE
Reiman EM
DJ
De Jager PL
BD
Bennett DA
Chapter II

Abstract

Summary of the research findings

Importance: While numerous genetic susceptibility loci have been identified for clinical Alzheimer disease (AD), it is important to establish whether these variants are risk factors for the underlying disease pathology, including neuritic plaques.

651 European and unknown ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

765
Total Participants
GWAS
Study Type
Yes
Replicated
114 individuals
Replication Participants
NR, European
Ancestry
U.S., Canada
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.