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GWAS Study

A genome-wide association study of myasthenia gravis.

Renton AE, Pliner HA, Provenzano C et al.

25643325 PubMed ID
GWAS Study Type
3839 Participants
35 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RA
Renton AE
PH
Pliner HA
PC
Provenzano C
EA
Evoli A
RR
Ricciardi R
NM
Nalls MA
MG
Marangi G
AY
Abramzon Y
AS
Arepalli S
CS
Chong S
HD
Hernandez DG
JJ
Johnson JO
BE
Bartoccioni E
SF
Scuderi F
MM
Maestri M
GJ
Gibbs JR
EE
Errichiello E
CA
Chiò A
RG
Restagno G
SM
Sabatelli M
MM
Macek M
SS
Scholz SW
CA
Corse A
CV
Chaudhry V
BM
Benatar M
BR
Barohn RJ
MA
McVey A
PM
Pasnoor M
DM
Dimachkie MM
RJ
Rowin J
KJ
Kissel J
FM
Freimer M
KH
Kaminski HJ
SD
Sanders DB
LB
Lipscomb B
MJ
Massey JM
CM
Chopra M
HJ
Howard JF
KW
Koopman WJ
NM
Nicolle MW
PR
Pascuzzi RM
PA
Pestronk A
WC
Wulf C
FJ
Florence J
BD
Blackmore D
SA
Soloway A
SZ
Siddiqi Z
MS
Muppidi S
WG
Wolfe G
RD
Richman D
MM
Mezei MM
JT
Jiwa T
OJ
Oger J
DD
Drachman DB
TB
Traynor BJ
Chapter II

Abstract

Summary of the research findings

Importance: Myasthenia gravis is a chronic, autoimmune, neuromuscular disease characterized by fluctuating weakness of voluntary muscle groups. Although genetic factors are known to play a role in this neuroimmunological condition, the genetic etiology underlying myasthenia gravis is not well understood.

972 European ancestry cases, 1,977 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

3839
Total Participants
GWAS
Study Type
Yes
Replicated
423 European ancestry cases, 467 European ancestry controls
Replication Participants
European
Ancestry
Italy
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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