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GWAS 2023-03-17

Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions.

Lindström S, Wang L et al.

J Natl Cancer Inst

The shared inherited genetic contribution to risk of different cancers is not fully known. In this s...

Cancer (pleiotropy)

909623

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-05

Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk.

Tian Y, Kim AE et al.

J Natl Cancer Inst

The use of menopausal hormone therapy (MHT) may interact with genetic variants to influence colorect...

Colorectal cancer x menopausal hormone therapy interaction

28486

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-02

Genetic analysis of lung cancer and the germline impact on somatic mutation burden.

Gabriel AAG, Atkins JR et al.

J Natl Cancer Inst

Germline genetic variation contributes to lung cancer (LC) susceptibility. Previous genome-wide asso...

Lung cancer or family history of lung cancer

329946

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-23

Different Pigmentation Risk Loci for High-Risk Monosomy 3 and Low-Risk Disomy 3 Uveal Melanomas.

Mobuchon L, Derrien AC et al.

J Natl Cancer Inst

Uveal melanoma (UM), a rare malignant tumor of the eye, is predominantly observed in populations of ...

Uveal melanoma

2024

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-07

Association of GATA3 polymorphisms with minimal residual disease and relapse risk in childhood acute lymphoblastic leukemia.

Zhang H, Liu AP et al.

J Natl Cancer Inst

Minimal residual disease (MRD) after induction therapy is one of the strongest prognostic factors in...

End-of-induction therapy minimal residual disease in childhood acute lymphoblastic leukemia

Replicated

3088

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-03

Genome-wide association study of susceptibility loci for TCF3-PBX1 acute lymphoblastic leukemia in children.

Lee SHR, Qian M et al.

J Natl Cancer Inst

Acute lymphoblastic leukemia (ALL) is the most common cancer in children. TCF3-PBX1 fusion defines a...

Childhood acute lymphoblastic leukemia (TCF3-PBX1 fusion)

Replicated

5640

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-12

Common susceptibility loci for male breast cancer.

Maguire S, Perraki E et al.

J Natl Cancer Inst

The etiology of male breast cancer (MBC) is poorly understood. In particular, the extent to which th...

Breast cancer (male)

Replicated

6836

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-23

Association of body mass index with colorectal cancer risk by genome-wide variants.

Campbell PT, Lin Y et al.

J Natl Cancer Inst

Body mass index (BMI) is a complex phenotype that may interact with genetic variants to influence co...

Colorectal cancer x BMI interaction (2df)

28475

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-16

Radiogenomics Consortium Genome-Wide Association Study Meta-analysis of Late Toxicity after Prostate Cancer Radiotherapy.

Kerns SL, Fachal L et al.

J Natl Cancer Inst

A total of 10%-20% of patients develop long-term toxicity following radiotherapy for prostate cancer...

Toxicity response to radiotherapy in prostate cancer (rectal bleeding) (time to event)

Replicated

3379

Participants

N/A

Studies

Details PubMed

GWAS 2019-04-02

Genome-wide association study of susceptibility loci for T-cell acute lymphoblastic leukemia in children.

Qian M, Zhao X et al.

J Natl Cancer Inst

Acute lymphoblastic leukemia (ALL) is the most common cancer in children and can arise in B or T lym...

T-cell acute lymphoblastic leukaemia

Replicated

19004

Participants

N/A

Studies

Details PubMed

GWAS 2018-12-12

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer.

Walsh N, Zhang H et al.

J Natl Cancer Inst

Genome-wide association studies (GWAS) identify associations of individual single-nucleotide polymor...

Pancreatic ductal adenocarcinoma

21536

Participants

N/A

Studies

Details PubMed

GWAS 2018-10-08

Genome-Wide Association Study of Susceptibility Loci for Radiation-Induced Brain Injury.

Wang TM, Shen GP et al.

J Natl Cancer Inst

Radiation-induced brain injury is a nonnegligible issue in the management of cancer patients treated...

Radiation-induced brain injury in nasopharyngeal carcinoma

Replicated

2942

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions.

Lindström S, Wang L et al.

J Natl Cancer Inst

Cancer (pleiotropy)

2023-03-17

Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk.

Tian Y, Kim AE et al.

J Natl Cancer Inst

Colorectal cancer x menopausal hormone therapy interaction

2022-05-05

Genetic analysis of lung cancer and the germline impact on somatic mutation burden.

Gabriel AAG, Atkins JR et al.

J Natl Cancer Inst

Lung cancer or family history of lung cancer

2022-05-02

Different Pigmentation Risk Loci for High-Risk Monosomy 3 and Low-Risk Disomy 3 Uveal Melanomas.

Mobuchon L, Derrien AC et al.

J Natl Cancer Inst

Uveal melanoma

2021-08-23

Association of GATA3 polymorphisms with minimal residual disease and relapse risk in childhood acute lymphoblastic leukemia.

Zhang H, Liu AP et al.

J Natl Cancer Inst

End-of-induction therapy minimal residual disease in childhood acute lymphoblastic leukemia

2020-09-07

Genome-wide association study of susceptibility loci for TCF3-PBX1 acute lymphoblastic leukemia in children.

Lee SHR, Qian M et al.

J Natl Cancer Inst

Childhood acute lymphoblastic leukemia (TCF3-PBX1 fusion)

2020-09-03

Common susceptibility loci for male breast cancer.

Maguire S, Perraki E et al.

J Natl Cancer Inst

Breast cancer (male)

2020-08-12

Association of body mass index with colorectal cancer risk by genome-wide variants.

Campbell PT, Lin Y et al.

J Natl Cancer Inst

Colorectal cancer x BMI interaction (2df)

2020-04-23

Radiogenomics Consortium Genome-Wide Association Study Meta-analysis of Late Toxicity after Prostate Cancer Radiotherapy.

Kerns SL, Fachal L et al.

J Natl Cancer Inst

Toxicity response to radiotherapy in prostate cancer (rectal bleeding) (time to event)

2019-05-16

Genome-wide association study of susceptibility loci for T-cell acute lymphoblastic leukemia in children.

Qian M, Zhao X et al.

J Natl Cancer Inst

T-cell acute lymphoblastic leukaemia

2019-04-02

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer.

Walsh N, Zhang H et al.

J Natl Cancer Inst

Pancreatic ductal adenocarcinoma

2018-12-12

Genome-Wide Association Study of Susceptibility Loci for Radiation-Induced Brain Injury.

Wang TM, Shen GP et al.

J Natl Cancer Inst

Radiation-induced brain injury in nasopharyngeal carcinoma

2018-10-08