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GWAS Study

Common susceptibility loci for male breast cancer.

Maguire S, Perraki E, Tomczyk K et al.

32785646 PubMed ID
GWAS Study Type
6836 Participants
72 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MS
Maguire S
PE
Perraki E
TK
Tomczyk K
JM
Jones ME
FO
Fletcher O
PM
Pugh M
WT
Winter T
TK
Thompson K
CR
Cooke R
TA
Trainer A
JP
James P
BS
Bojesen S
FH
Flyger H
NH
Nevanlinna H
MJ
Mattson J
FE
Friedman E
LY
Laitman Y
PD
Palli D
MG
Masala G
ZI
Zanna I
OL
Ottini L
SV
Silvestri V
HA
Hollestelle A
HM
Hooning MJ
NS
Novaković S
KM
Krajc M
GM
Gago-Dominguez M
CJ
Castelao JE
OH
Olsson H
HI
Hedenfalk I
SE
Saloustros E
GV
Georgoulias V
ED
Easton DF
PP
Pharoah P
DA
Dunning AM
BD
Bishop DT
NS
Neuhausen SL
SL
Steele L
AA
Ashworth A
GC
Garcia Closas M
HR
Houlston R
SA
Swerdlow A
ON
Orr N
Chapter II

Abstract

Summary of the research findings

The etiology of male breast cancer (MBC) is poorly understood. In particular, the extent to which the genetic basis of MBC differs from female breast cancer (FBC) is unknown. A previous genome-wide association study of MBC identified 2 predisposition loci for the disease, both of which were also associated with risk of FBC.

1,380 European ancestry cases, 3,620 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

6836
Total Participants
GWAS
Study Type
Yes
Replicated
810 European ancestry cases, 1,026 European ancestry controls
Replication Participants
European
Ancestry
U.K., Israel, Finland, Greece, Italy, Netherlands, Slovenia, Spain, Sweden, Australia, New Zealand
Recruitment Country
Chapter IV

AI-Generated Summary

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