Menu
GWAS Study

A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose.

Paterson AD, Waggott D, Boright AP et al.

19875614 PubMed ID
GWAS Study Type
2686 Participants
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PA
Paterson AD
WD
Waggott D
BA
Boright AP
HS
Hosseini SM
SE
Shen E
SM
Sylvestre MP
WI
Wong I
BB
Bharaj B
CP
Cleary PA
LJ
Lachin JM
BJ
Below JE
ND
Nicolae D
CN
Cox NJ
CA
Canty AJ
SL
Sun L
BS
Bull SB
Chapter II

Abstract

Summary of the research findings

Objective: Glycemia is a major risk factor for the development of long-term complications in type 1 diabetes; however, no specific genetic loci have been identified for glycemic control in individuals with type 1 diabetes. To identify such loci in type 1 diabetes, we analyzed longitudinal repeated measures of A1C from the Diabetes Control and Complications Trial.

667 European ancestry conventional treatment cases, 637 European ancestry intensive treatment cases

Chapter III

Study Statistics

Key metrics and study information

2686
Total Participants
GWAS
Study Type
Yes
Replicated
1,382 European ancestry cases
Replication Participants
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.