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GWAS Study

A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level.

Pattaro C, De Grandi A, Vitart V et al.

20222955 PubMed ID
GWAS Study Type
6041 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PC
Pattaro C
DG
De Grandi A
VV
Vitart V
HC
Hayward C
FA
Franke A
AY
Aulchenko YS
JA
Johansson A
WS
Wild SH
MS
Melville SA
IA
Isaacs A
PO
Polasek O
ED
Ellinghaus D
KI
Kolcic I
NU
Nöthlings U
ZL
Zgaga L
ZT
Zemunik T
GC
Gnewuch C
SS
Schreiber S
CS
Campbell S
HN
Hastie N
BM
Boban M
MT
Meitinger T
OB
Oostra BA
RP
Riegler P
MC
Minelli C
WA
Wright AF
CH
Campbell H
VD
van Duijn CM
GU
Gyllensten U
WJ
Wilson JF
KM
Krawczak M
RI
Rudan I
PP
Pramstaller PP
Chapter II

Abstract

Summary of the research findings

Serum creatinine (S CR) is the most important biomarker for a quick and non-invasive assessment of kidney function in population-based surveys. A substantial proportion of the inter-individual variability in S CR level is explicable by genetic factors.

4,006 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

6041
Total Participants
GWAS
Study Type
Yes
Replicated
2,035 European ancestry individuals
Replication Participants
European
Ancestry
Sweden, Italy, Netherlands, U.K., Croatia, Germany
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.