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GWAS Study

Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations.

Du R, Litonjua AA, Tantisira KG et al.

22051697 PubMed ID
GWAS Study Type
979 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DR
Du R
LA
Litonjua AA
TK
Tantisira KG
LJ
Lasky-Su J
SS
Sunyaev SR
KB
Klanderman BJ
CJ
Celedón JC
AL
Avila L
SM
Soto-Quiros ME
WS
Weiss ST
Chapter II

Abstract

Summary of the research findings

It has recently been shown that vitamin D deficiency can increase asthma development and severity and that variations in vitamin D receptor genes are associated with asthma susceptibility.

395 European ancestry child cases

Chapter III

Study Statistics

Key metrics and study information

979
Total Participants
GWAS
Study Type
Yes
Replicated
584 Hispanic child cases
Replication Participants
Hispanic or Latin American, European
Ancestry
Costa Rica
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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