Clinical and genetic correlates of growth differentiation factor 15 in the community.
Ho JE, Mahajan A, Chen MH et al.
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Abstract
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Growth differentiation factor 15 (GDF15), a stress-responsive cytokine produced in cardiovascular cells under conditions of inflammation and oxidative stress, is emerging as an important prognostic marker in individuals with and without existing cardiovascular disease (CVD). We therefore examined the clinical and genetic correlates of circulating GDF15 concentrations, which have not been investigated collectively.
3,889 European ancestry individuals
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