Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease.
Huertas-Vazquez A, Nelson CP, Guo X et al.
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Abstract
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Recent genome-wide association studies (GWAS) have identified novel loci associated with sudden cardiac death (SCD). Despite this progress, identified DNA variants account for a relatively small portion of overall SCD risk, suggesting that additional loci contributing to SCD susceptibility await discovery. The objective of this study was to identify novel DNA variation associated with SCD in the context of coronary artery disease (CAD).
948 European ancestry cases, 3,050 European ancestry controls
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