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GWAS Study

A genome-wide association study (GWAS) for bronchopulmonary dysplasia.

Wang H, St Julien KR, Stevenson DK et al.

23897914 PubMed ID
GWAS Study Type
2521 Participants
63 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WH
Wang H
SJ
St Julien KR
SD
Stevenson DK
HT
Hoffmann TJ
WJ
Witte JS
LL
Lazzeroni LC
KM
Krasnow MA
QC
Quaintance CC
OJ
Oehlert JW
JL
Jelliffe-Pawlowski LL
GJ
Gould JB
SG
Shaw GM
OH
O'Brodovich HM
Chapter II

Abstract

Summary of the research findings

Objective: Twin studies suggest that heritability of moderate-severe bronchopulmonary dysplasia (BPD) is 53% to 79%, we conducted a genome-wide association study (GWAS) to identify genetic variants associated with the risk for BPD.

117 African American newborn cases, 108 African American newborn controls, 448 Hispanic newborn cases, 460 Hispanic newborn controls, 74 Asian or Pacific Islander ancestry newborn cases, 93 Asian or Pacific Islander ancestry newborn controls, 174 European ancestry newborn cases, 216 European ancestry newborn controls, 14 newborn cases, 22 newborn controls

Chapter III

Study Statistics

Key metrics and study information

2521
Total Participants
GWAS
Study Type
Yes
Replicated
371 newborn cases, 424 newborn controls
Replication Participants
European, African American or Afro-Caribbean, Other, Hispanic or Latin American, African American or Afro-Caribbean, European, Hispanic or Latin American, Oceanian, Asian unspecified, Other, Oceanian, Asian unspecified
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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