Human immunotypes impose selection on viral genotypes through viral epitope specificity.
Gabrielaite M, Bennedbæk M, Zucco AG et al.
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Abstract
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Understanding the genetic interplay between human hosts and infectious pathogens is crucial for how we interpret virulence factors. Here, we tested for associations between HIV and host genetics, and interactive genetic effects on viral load (VL) in HIV-positive antiretroviral treatment-naive clinical trial participants.
21 Asian ancestry individuals, 432 African ancestry individuals, 382 Hispanic or Latin American individuals, 1,250 European ancestry individuals, 37 individuals
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