Host Genetic Risk Factors for Chlamydia trachomatis-Related Infertility in Women.
Zheng X, Zhong W, O'Connell CM et al.
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Abstract
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Chlamydia trachomatis (Ct) infection ascending to the upper genital tract can cause infertility. Direct association of genetic variants as contributors is challenging because infertility may not be diagnosed until years after infection. Investigating the intermediate trait of ascension bridges this gap.
74 European ancestry cases, 208 European ancestry controls, 33 Black cases, 52 Black controls, 6 Hispanic or Latino cases, 8 Hispanic or Latino controls, 4 Asian ancestry cases, 8 Asian ancestry controls, 2 cases, 1 controls
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