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GWAS Study

VEGF-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease.

Davidsson P, Eketjäll S, Eriksson N et al.

36869765 PubMed ID
GWAS Study Type
4910 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DP
Davidsson P
ES
Eketjäll S
EN
Eriksson N
WA
Walentinsson A
BR
Becker RC
CA
Cavallin A
BA
Bogstedt A
CA
Collén A
HC
Held C
JS
James S
SA
Siegbahn A
SR
Stewart R
SR
Storey RF
WH
White H
WL
Wallentin L
Chapter II

Abstract

Summary of the research findings

Aims: The vascular endothelial growth factor (VEGF) family is involved in pathophysiological mechanisms underlying cardiovascular (CV) diseases. The aim of this study was to investigate the associations between circulating VEGF ligands and/or soluble receptors and CV outcome in patients with acute coronary syndrome (ACS) and chronic coronary syndrome (CCS).

1,907 European ancestry individuals with acute coronary syndrome, 20 black individuals with acute coronary syndrome, 39 Asian ancestry individuals with acute coronary syndrome

Chapter III

Study Statistics

Key metrics and study information

4910
Total Participants
GWAS
Study Type
Yes
Replicated
2,944 individuals with chronic coronary syndrome
Replication Participants
European, African unspecified, Asian unspecified
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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