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GWAS Study

Elucidation of the genetic causes of bicuspid aortic valve disease.

Gehlen J, Stundl A, Debiec R et al.

35727948 PubMed ID
GWAS Study Type
17904 Participants
120 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GJ
Gehlen J
SA
Stundl A
DR
Debiec R
FF
Fontana F
KM
Krane M
SD
Sharipova D
NC
Nelson CP
AB
Al-Kassou B
GA
Giel AS
SJ
Sinning JM
BC
Bruenger CMH
ZC
Zelck CF
KL
Koebbe LL
BP
Braund PS
WT
Webb TR
HS
Hetherington S
ES
Ensminger S
FB
Fujita B
MS
Mohamed SA
SM
Shrestha M
KH
Krueger H
SM
Siepe M
KF
Kari FA
NP
Nordbeck P
BL
Buravezky L
KM
Kelm M
VV
Veulemans V
AM
Adam M
BS
Baldus S
LK
Laugwitz KL
HY
Haas Y
KM
Karck M
MU
Mehlhorn U
CL
Conzelmann LO
BI
Breitenbach I
LC
Lebherz C
UP
Urbanski P
KW
Kim WK
KJ
Kandels J
ED
Ellinghaus D
NU
Nowak-Goettl U
HP
Hoffmann P
WF
Wirth F
DS
Doppler S
LH
Lahm H
DM
Dreßen M
VS
von Scheidt M
KK
Knoll K
KT
Kessler T
HC
Hengstenberg C
SH
Schunkert H
NG
Nickenig G
NM
Nöthen MM
BA
Bolger AP
AS
Abdelilah-Seyfried S
SN
Samani NJ
EJ
Erdmann J
TT
Trenkwalder T
SJ
Schumacher J
Chapter II

Abstract

Summary of the research findings

Aims: The present study aims to characterize the genetic risk architecture of bicuspid aortic valve (BAV) disease, the most common congenital heart defect.

2,236 European ancestry cases, 11,604 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

17904
Total Participants
GWAS
Study Type
Yes
Replicated
421 European ancestry cases, 3,643 European ancestry controls
Replication Participants
European
Ancestry
U.K., Germany
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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