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GWAS Study

Genetic risk of prostate cancer in Ugandan men.

Du Z, Lubmawa A, Gundell S et al.

29356057 PubMed ID
GWAS Study Type
1040 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DZ
Du Z
LA
Lubmawa A
GS
Gundell S
WP
Wan P
NC
Nalukenge C
MP
Muwanga P
LM
Lutalo M
ND
Nansereko D
NO
Ndaruhutse O
KM
Katuku M
NR
Nassanga R
AF
Asiimwe F
MB
Masaba B
KS
Kaggwa S
ND
Namuguzi D
KV
Kiddu V
MG
Mutema G
CD
Conti DV
LA
Luke A
JK
Job K
HD
Henry DM
HC
Haiman CA
WS
Watya S
Chapter II

Abstract

Summary of the research findings

Men of African-ancestry have elevated prostate cancer (PCa) incidence and mortality compared to men of other racial groups. There is support for a genetic contribution to this disparity, with evidence of genetic heterogeneity in the underlying risk alleles between populations. Studies of PCa among African men may inform the contribution of genetic risk factors to the elevated disease burden in this population.

560 Ugandan ancestry cases, 480 Ugandan ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1040
Total Participants
GWAS
Study Type
No
Replicated
Sub-Saharan African
Ancestry
Uganda
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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