The Genetic Determinants of Aortic Distention.
Pirruccello JP, Rämö JT, Choi SH et al.
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Abstract
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As the largest conduit vessel, the aorta is responsible for the conversion of phasic systolic inflow from ventricular ejection into more continuous peripheral blood delivery. Systolic distention and diastolic recoil conserve energy and are enabled by the specialized composition of the aortic extracellular matrix. Aortic distensibility decreases with age and vascular disease.
32,639 European or unknown ancestry individuals
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