Menu
Research Publication

Earliest modern human genomes constrain timing of Neanderthal admixture.

Sümer Arev P, AP Rougier, Hélène H et al.

39667410 PubMed ID
67 Authors
2025-02-12 Published
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SA
Sümer Arev P
AR
AP Rougier
HH
Hélène H
VV
Villalba-Mouco Vanessa
VH
V Huang
YY
Yilei Y
IL
Iasi Leonardo N M
LE
LNM Essel
EE
Elena E
BM
Bossoms Mesa Alba
AF
A Furtwaengler
AA
Anja A
PS
Peyrégne Stéphane
SD
S de Filippo
CC
Cesare C
RA
Rohrlach Adam B
AP
AB Pierini
FF
Federica F
MF
Mafessoni Fabrizio
FF
F Fewlass
HH
Helen H
ZE
Zavala Elena I
EM
EI Mylopotamitaki
DD
Dorothea D
BR
Bianco Raffaela A
RS
RA Schmidt
AA
Anna A
ZJ
Zorn Julia
JN
J Nickel
BB
Birgit B
PA
Patova Anna
AP
A Posth
CC
Cosimo C
SG
Smith Geoff M
GR
GM Ruebens
KK
Karen K
SV
Sinet-Mathiot Virginie
VS
V Stoessel
AA
Alexander A
DH
Dietl Holger
HO
H Orschiedt
JJ
Jörg J
KJ
Kelso Janet
JZ
J Zeberg
HH
Hugo H
BK
Bos Kirsten I
KW
KI Welker
FF
Frido F
WM
Weiss Marcel
MM
M McPherron
SP
Shannon P SP
ST
Schüler Tim
TH
T Hublin
JJ
Jean-Jacques JJ
VP
Velemínský Petr
PB
P Brůžek
JJ
Jaroslav J
PB
Peter Benjamin M
BM
BM Meyer
MM
Matthias M
MH
Meller Harald
HR
H Ringbauer
HH
Harald H
HM
Hajdinjak Mateja
MP
M Prüfer
KK
Kay K
KJ
Krause Johannes
Chapter II

Abstract

Summary of the research findings

Modern humans arrived in Europe more than 45,000 years ago, overlapping at least 5,000 years with Neanderthals1-4. Limited genomic data from these early modern humans have shown that at least two genetically distinct groups inhabited Europe, represented by Zlatý kůň, Czechia3 and Bacho Kiro, Bulgaria2. Here we deepen our understanding of early modern humans by analysing one high-coverage genome and five low-coverage genomes from approximately 45,000-year-old remains from Ilsenhöhle in Ranis, Germany4, and a further high-coverage genome from Zlatý kůň. We show that distant familial relationships link the Ranis and Zlatý kůň individuals and that they were part of the same small, isolated population that represents the deepest known split from the Out-of-Africa lineage. Ranis genomes harbour Neanderthal segments that originate from a single admixture event shared with all non-Africans that we date to approximately 45,000-49,000 years ago. This implies that ancestors of all non-Africans sequenced so far resided in a common population at this time, and further suggests that modern human remains older than 50,000 years from outside Africa represent different non-African populations.

Chapter III

Analysis

Comprehensive review of ancestry and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Summary

Key Findings

Ancestry Insights

Traits Analysis

Historical Context

Scientific Assessment