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GWAS Study

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.

Li H, Wetten S, Li L et al.

17998437 PubMed ID
GWAS Study Type
2156 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LH
Li H
WS
Wetten S
LL
Li L
SJ
St Jean PL
UR
Upmanyu R
SL
Surh L
HD
Hosford D
BM
Barnes MR
BJ
Briley JD
BM
Borrie M
CN
Coletta N
DR
Delisle R
DD
Dhalla D
EM
Ehm MG
FH
Feldman HH
FL
Fornazzari L
GS
Gauthier S
GN
Goodgame N
GD
Guzman D
HS
Hammond S
HP
Hollingworth P
HG
Hsiung GY
JJ
Johnson J
KD
Kelly DD
KR
Keren R
KA
Kertesz A
KK
King KS
LS
Lovestone S
LI
Loy-English I
MP
Matthews PM
OM
Owen MJ
PM
Plumpton M
PW
Pryse-Phillips W
PR
Prinjha RK
RJ
Richardson JC
SA
Saunders A
SA
Slater AJ
SG
St George-Hyslop PH
SS
Stinnett SW
SJ
Swartz JE
TR
Taylor RL
WJ
Wherrett J
WJ
Williams J
YD
Yarnall DP
GR
Gibson RA
IM
Irizarry MC
ML
Middleton LT
RA
Roses AD
Chapter II

Abstract

Summary of the research findings

Objective: To identify single-nucleotide polymorphisms (SNPs) associated with risk and age at onset of Alzheimer disease (AD) in a genomewide association study of 469 438 SNPs.

753 European ancestry cases, 736 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

2156
Total Participants
GWAS
Study Type
Yes
Replicated
418 European ancestry cases, 249 European ancestry controls
Replication Participants
European
Ancestry
Canada, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.