COL4A1 is associated with arterial stiffness by genome-wide association scan.
Tarasov KV, Sanna S, Scuteri A et al.
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Abstract
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Pulse wave velocity (PWV), a noninvasive index of central arterial stiffness, is a potent predictor of cardiovascular mortality and morbidity. Heritability and linkage studies have pointed toward a genetic component affecting PWV. We conducted a genome-wide association study to identify single-nucleotide polymorphisms (SNPs) associated with PWV.
4,221 Sardinian individuals
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