Menu
GWAS Study

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.

Nalls MA, Plagnol V, Hernandez DG et al.

21292315 PubMed ID
GWAS Study Type
33412 Participants
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NM
Nalls MA
PV
Plagnol V
HD
Hernandez DG
SM
Sharma M
SU
Sheerin UM
SM
Saad M
SJ
Simón-Sánchez J
SC
Schulte C
LS
Lesage S
SS
Sveinbjörnsdóttir S
SK
Stefánsson K
MM
Martinez M
HJ
Hardy J
HP
Heutink P
BA
Brice A
GT
Gasser T
SA
Singleton AB
WN
Wood NW
Chapter II

Abstract

Summary of the research findings

Genome-wide association studies (GWAS) for Parkinson's disease have linked two loci (MAPT and SNCA) to risk of Parkinson's disease. We aimed to identify novel risk loci for Parkinson's disease.

5,333 European ancestry cases, 12,019 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

33412
Total Participants
GWAS
Study Type
Yes
Replicated
7,053 cases, 9,007 controls
Replication Participants
European, NR, European
Ancestry
U.S., Germany, U.K., France, Iceland, Netherlands
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.