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GWAS Study

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.

Nalls MA, Plagnol V, Hernandez DG et al.

21292315 PubMed ID
GWAS Study Type
33412 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NM
Nalls MA
PV
Plagnol V
HD
Hernandez DG
SM
Sharma M
SU
Sheerin UM
SM
Saad M
SJ
Simón-Sánchez J
SC
Schulte C
LS
Lesage S
SS
Sveinbjörnsdóttir S
SK
Stefánsson K
MM
Martinez M
HJ
Hardy J
HP
Heutink P
BA
Brice A
GT
Gasser T
SA
Singleton AB
WN
Wood NW
Chapter II

Abstract

Summary of the research findings

Genome-wide association studies (GWAS) for Parkinson's disease have linked two loci (MAPT and SNCA) to risk of Parkinson's disease. We aimed to identify novel risk loci for Parkinson's disease.

5,333 European ancestry cases, 12,019 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

33412
Total Participants
GWAS
Study Type
Yes
Replicated
7,053 cases, 9,007 controls
Replication Participants
European, NR, European
Ancestry
U.S., Germany, U.K., France, Iceland, Netherlands
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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