Pooled genome-wide analysis to identify novel risk loci for pediatric allergic asthma.
Ricci G, Astolfi A, Remondini D et al.
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Genome-wide association studies of pooled DNA samples were shown to be a valuable tool to identify candidate SNPs associated to a phenotype. No such study was up to now applied to childhood allergic asthma, even if the very high complexity of asthma genetics is an appropriate field to explore the potential of pooled GWAS approach.
135 European ancestry asthma child cases, 134 European ancestry rhinoconjunctivitis child cases
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