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GWAS Study

Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08.

Gregersen PK, Kosoy R, Lee AT et al.

23055271 PubMed ID
GWAS Study Type
9569 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GP
Gregersen PK
KR
Kosoy R
LA
Lee AT
LJ
Lamb J
SJ
Sussman J
MD
McKee D
SK
Simpfendorfer KR
PR
Pirskanen-Matell R
PF
Piehl F
PQ
Pan-Hammarstrom Q
VJ
Verschuuren JJ
TM
Titulaer MJ
NE
Niks EH
MA
Marx A
SP
Ströbel P
TB
Tackenberg B
PM
Pütz M
MA
Maniaol A
EA
Elsais A
TC
Tallaksen C
HH
Harbo HF
LB
Lie BA
RS
Raychaudhuri S
DB
de Bakker PI
MA
Melms A
GH
Garchon HJ
WN
Willcox N
HL
Hammarstrom L
SM
Seldin MF
Chapter II

Abstract

Summary of the research findings

Objective: The objective of this study is to comprehensively define the genetic basis of early onset myasthenia gravis (EOMG).

400 European ancestry cases, 5,505 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

9569
Total Participants
GWAS
Study Type
Yes
Replicated
249 European ancestry cases, 3,415 European ancestry controls
Replication Participants
European
Ancestry
Sweden, Netherlands, U.K., France, Norway, Germany
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.