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GWAS Study

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.

Urabe Y, Ochi H, Kato N et al.

23321320 PubMed ID
GWAS Study Type
6472 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

UY
Urabe Y
OH
Ochi H
KN
Kato N
KV
Kumar V
TA
Takahashi A
MR
Muroyama R
HN
Hosono N
OM
Otsuka M
TR
Tateishi R
LP
Lo PH
TC
Tanikawa C
OM
Omata M
KK
Koike K
MD
Miki D
AH
Abe H
KN
Kamatani N
TJ
Toyota J
KH
Kumada H
KM
Kubo M
CK
Chayama K
NY
Nakamura Y
MK
Matsuda K
Chapter II

Abstract

Summary of the research findings

Background & aims: We performed a genome-wide association study (GWAS) of hepatitis C virus (HCV)-induced liver cirrhosis (LC) to identify predictive biomarkers for the risk of LC in patients with chronic hepatitis C (CHC).

682 Japanese ancestry cases, 1,045 Japanese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

6472
Total Participants
GWAS
Study Type
Yes
Replicated
936 Japanese ancestry cases, 3,809 Japanese ancestry controls
Replication Participants
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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