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GWAS Study

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.

Wilman HR, Parisinos CA, Atabaki-Pasdar N et al.

31226389 PubMed ID
GWAS Study Type
9802 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WH
Wilman HR
PC
Parisinos CA
AN
Atabaki-Pasdar N
KM
Kelly M
TE
Thomas EL
NS
Neubauer S
MA
Mahajan A
HA
Hingorani AD
PR
Patel RS
HH
Hemingway H
FP
Franks PW
BJ
Bell JD
BR
Banerjee R
YH
Yaghootkar H
Chapter II

Abstract

Summary of the research findings

Background & aims: Excess liver iron content is common and is linked to the risk of hepatic and extrahepatic diseases. We aimed to identify genetic variants influencing liver iron content and use genetics to understand its link to other traits and diseases.

8,289 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

9802
Total Participants
GWAS
Study Type
Yes
Replicated
1,513 European ancestry individuals
Replication Participants
European
Ancestry
U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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