Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes.
Glessner JT, Ningappa MB, Ngo KA et al.
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Background & aims: Biliary atresia (BA) is poorly understood and leads to liver transplantation (LT), with the requirement for and associated risks of lifelong immunosuppression, in most children. We performed a genome-wide association study (GWAS) to determine the genetic basis of BA.
811 European ancestry cases, 4,654 European ancestry controls
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