GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Broer L, Buchman AS, Deelen J et al.
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Abstract
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The genetic contribution to longevity in humans has been estimated to range from 15% to 25%. Only two genes, APOE and FOXO3, have shown association with longevity in multiple independent studies.
6,036 European ancestry cases, 3,757 European ancestry controls
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