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GWAS Study

Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations.

Dashti HS, Shea MK, Smith CE et al.

25411281 PubMed ID
GWAS Study Type
2138 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DH
Dashti HS
SM
Shea MK
SC
Smith CE
TT
Tanaka T
HA
Hruby A
RK
Richardson K
WT
Wang TJ
NM
Nalls MA
GX
Guo X
LY
Liu Y
YJ
Yao J
LD
Li D
JW
Johnson WC
BE
Benjamin EJ
KS
Kritchevsky SB
SD
Siscovick DS
OJ
Ordovás JM
BS
Booth SL
Chapter II

Abstract

Summary of the research findings

Poor vitamin K status is linked to greater risk of several chronic diseases. Age, sex, and diet are determinants of circulating vitamin K; however, there is still large unexplained interindividual variability in vitamin K status. Although a strong genetic component has been hypothesized, this has yet to be examined by a genome-wide association (GWA) study.

2,138 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

2138
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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