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GWAS Study

Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.

Chauhan G

27068588 PubMed ID
GWAS Study Type
152433 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CG
Chauhan G
Chapter II

Abstract

Summary of the research findings

Genetic determinants of stroke, the leading neurological cause of death and disability, are poorly understood and have seldom been explored in the general population. Our aim was to identify additional loci for stroke by doing a meta-analysis of genome-wide association studies.

3,028 European ancestry cases, 80,613 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

152433
Total Participants
GWAS
Study Type
Yes
Replicated
2,284 European ancestry cases, 17,184 European ancestry controls, 16,851 African unspecified, Hispanic and European ancestry cases, 32,473 African unspecified, Hispanic and European ancestry controls
Replication Participants
African unspecified, European, Hispanic or Latin American, European
Ancestry
U.S., Finland, France, Germany, Netherlands, Sweden
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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