Genome-wide search identifies a gene-gene interaction between 20p13 and 2q14 in asthma.
Murk W, DeWan AT
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Abstract
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Many studies have attempted to identify gene-gene interactions affecting asthma susceptibility. However, these studies have typically used candidate gene approaches in limiting the genetic search space, and there have been few searches for gene-gene interactions on a genome-wide scale. We aimed to conduct a genome-wide gene-gene interaction study for asthma, using data from the GABRIEL Consortium.
802 European ancestry cases, 823 European ancestry controls
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