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GWAS Study

Genome Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor.

Bime C, Pouladi N, Sammani S et al.

29425463 PubMed ID
GWAS Study Type
1363 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BC
Bime C
PN
Pouladi N
SS
Sammani S
BK
Batai K
CN
Casanova N
ZT
Zhou T
KC
Kempf CL
SX
Sun X
CS
Camp SM
WT
Wang T
KR
Kittles RA
LY
Lussier YA
JT
Jones TK
RJ
Reilly JP
MN
Meyer NJ
CJ
Christie JD
KJ
Karnes JH
GM
Gonzalez-Garay M
CD
Christiani DC
YC
Yates CR
WM
Wurfel MM
MG
Meduri GU
GJ
Garcia JGN
Chapter II

Abstract

Summary of the research findings

Rationale: Genetic factors are involved in acute respiratory distress syndrome (ARDS) susceptibility. Identification of novel candidate genes associated with increased risk and severity will improve our understanding of ARDS pathophysiology and enhance efforts to develop novel preventive and therapeutic approaches.

232 African American ancestry cases, 162 African American ancestry controls with sepsis or other risk factors

Chapter III

Study Statistics

Key metrics and study information

1363
Total Participants
GWAS
Study Type
Yes
Replicated
140 African American cases, 269 European ancestry cases, 222 African American ancestry controls with sepsis, 338 European ancestry controls with sepsis
Replication Participants
African American or Afro-Caribbean, European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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