GWAS of QRS duration identifies new loci specific to Hispanic/Latino populations.
Swenson BR, Louie T, Lin HJ et al.
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Abstract
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The electrocardiographically quantified QRS duration measures ventricular depolarization and conduction. QRS prolongation has been associated with poor heart failure prognosis and cardiovascular mortality, including sudden death. While previous genome-wide association studies (GWAS) have identified 32 QRS SNPs across 26 loci among European, African, and Asian-descent populations, the genetics of QRS among Hispanics/Latinos has not been previously explored.
15,124 Hispanic or Latin American individuals
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