Meta-analysis of 26,638 Individuals Identifies Two Genetic Loci Associated with Left Ventricular Ejection Fraction.
Choquet H, Thai KK, Jiang C et al.
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Abstract
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Left ventricular ejection fraction (EF) is an indicator of cardiac function, usually assessed in individuals with heart failure and other cardiac conditions. Although family studies indicate that EF has an important genetic component with heritability estimates up to 0.61, to date only 6 EF-associated loci have been reported.
18,670 European ancestry individuals, 1,207 East Asian ancestry individuals, 1,514 Hispanic/Latino individuals, 764 African American individuals
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