Genetic determinants of ferritin, haemoglobin levels and haemoglobin trajectories: results from Donor InSight.
Timmer T, Tanck M, Penkett C et al.
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Abstract
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Background and objectives: Blood donors might develop iron deficiency as approximately 250 mg of iron is lost with every donation. Susceptibility to iron deficiency and low haemoglobin levels differs between individuals, which might be due to genetic variation. Therefore, the aim of this study was to investigate associations between single nucleotide polymorphisms (SNPs) and haemoglobin trajectories, haemoglobin levels and ferritin levels in blood donors.
2,649 European ancestry individuals
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