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GWAS Study

Multi-ethnic genome-wide and HLA association study of total serum IgE.

Daya M, Cox C, Acevedo N et al.

34536413 PubMed ID
GWAS Study Type
21901 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DM
Daya M
CC
Cox C
AN
Acevedo N
BM
Boorgula MP
CM
Campbell M
CS
Chavan S
CM
Cho MH
DG
David GL
KP
Kachroo P
LJ
Lasky-Su J
LX
Li X
MC
McHugh CP
QD
Qiao D
RN
Rafaels N
BL
Beck LA
BE
Bleecker ER
CL
Caraballo L
CA
Cupples AL
FC
Figueiredo CA
GR
Gallo RL
HJ
Hanifin J
HN
Hansel NN
HT
Hata TR
HC
Hersh CP
KJ
Knight-Madden J
LD
Leung DYM
GE
Guttman-Yassky E
MD
Meyers DA
OG
O'Connor G
OC
Ober C
OP
Ong PY
OV
Ortega VE
PA
Paller AS
PN
Putcha N
RR
Reed RM
SL
Schneider LC
SE
Silverman EK
SM
Slifka MK
SJ
Spergel JM
VR
Vasan RS
VK
Viaud-Martinez KA
WH
Watson H
WS
Weiss ST
RI
Ruczinski I
BT
Beaty TH
MR
Mathias RA
BK
Barnes KC
Chapter II

Abstract

Summary of the research findings

Total serum IgE (tIgE) is an important intermediate phenotype of allergic disease. Whole genome genetic association studies across ancestries may identify important determinants of IgE.

5,008 African American individuals, 12,908 European ancestry individuals, 3,985 Hispanic individuals

Chapter III

Study Statistics

Key metrics and study information

21901
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean, European, Hispanic or Latin American
Ancestry
Colombia, Brazil, Peru, Costa Rica, U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.