Shared genetics between classes of obesity and psychiatric disorders: A large-scale genome-wide cross-trait analysis.
Ding H, Ouyang M, Wang J et al.
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Abstract
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Aims: Epidemiological studies demonstrate an association between classes of obesity and psychiatric disorders, although little is known about shared genetics and causality of association. Thus, we aimed to investigate shared genetics and causal link between different classes of obesity and psychiatric disorders.
32,858 European ancestry obesity class I cases, 19,099 European ancestry cases, 16,992 European ancestry anorexia nervosa cases, 170,756 European ancestry major depressive disorder cases, 2,688 European ancestry obsessive-compulsive disorder cases, 492038 European ancestry controls
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