Interactions between genetic variants and environmental risk factors are associated with the severity of pelvic organ prolapse.
Li L, Zhao G, Wu J et al.
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Abstract
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Objective: Both environmental and genetic risk factors contribute to pelvic organ prolapse (POP). No genome-wide study has investigated the gene-environment (G × E) interactions. In this study, we aim to identify single nucleotide polymorphisms (SNPs) that may interact with the potential environmental factors, maximum birth weight, and age in Chinese women.
707 Han Chinese ancestry females
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