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GWAS Study

Genetic Variants Associated With Hidradenitis Suppurativa.

Sun Q, Broadaway KA, Edmiston SN et al.

37494057 PubMed ID
GWAS Study Type
834662 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SQ
Sun Q
BK
Broadaway KA
ES
Edmiston SN
FK
Fajgenbaum K
MT
Miller-Fleming T
WL
Westerkam LL
MM
Melendez-Gonzalez M
BH
Bui H
BF
Blum FR
LB
Levitt B
LL
Lin L
HH
Hao H
HK
Harris KM
LZ
Liu Z
TN
Thomas NE
CN
Cox NJ
LY
Li Y
MK
Mohlke KL
SC
Sayed CJ
Chapter II

Abstract

Summary of the research findings

Importance: Hidradenitis suppurativa (HS) is a common and severely morbid chronic inflammatory skin disease that is reported to be highly heritable. However, the genetic understanding of HS is insufficient, and limited genome-wide association studies (GWASs) have been performed for HS, which have not identified significant risk loci.

1,640 European ancestry, African American or Afro-Caribbean, NR cases, 756,393 European ancestry, African American or Afro-Caribbean, NR controls

Chapter III

Study Statistics

Key metrics and study information

834662
Total Participants
GWAS
Study Type
Yes
Replicated
189 European ancestry cases, 64,234 European ancestry controls, 101 African American or Afro-Caribbean cases, 12,105 African American or Afro-Caribbean controls
Replication Participants
European, African American or Afro-Caribbean, NR, European, African American or Afro-Caribbean
Ancestry
U.S., Finland, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.