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GWAS Study

Genome-wide Analysis of Motor Progression in Parkinson Disease.

Martínez Carrasco A, Real R, Lawton M et al.

37560120 PubMed ID
GWAS Study Type
3572 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MC
Martínez Carrasco A
RR
Real R
LM
Lawton M
HR
Hertfelder Reynolds R
TM
Tan M
WL
Wu L
WN
Williams N
CC
Carroll C
CJ
Corvol JC
HM
Hu M
GD
Grosset D
HJ
Hardy J
RM
Ryten M
BY
Ben-Shlomo Y
SM
Shoai M
MH
Morris HR
Chapter II

Abstract

Summary of the research findings

Background and objectives: The genetic basis of Parkinson disease (PD) motor progression is largely unknown. Previous studies of the genetics of PD progression have included small cohorts and shown a limited overlap with genetic PD risk factors from case-control studies. Here, we have studied genomic variation associated with PD motor severity and early-stage progression in large longitudinal cohorts to help to define the biology of PD progression and potential new drug targets.

3,572 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

3572
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S., U.K., France
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.