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Research Publication

Ancient genomes from Ladakh reveal 2800-year-old mixture between Tibetans and South Asians

Nick Patterson, Veena Mushrif-Tripathy, Quentin Devers et al.

9 Authors
2026-01-30 Published
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NP
Nick Patterson
VM
Veena Mushrif-Tripathy
QD
Quentin Devers
LQ
Lijun Qiu
SD
Sonam Dolma
GS
Gregory Soos
SM
Swapan Mallick
NR
Nadin Rohland
DR
David Reich
Chapter II

Abstract

Summary of the research findings

Reconstructing population history is harder in South Asia than in many other world regions due to a paucity of ancient DNA. We report genome-wide data for ten individuals from Old Lady Spider Cave, which lies 4000 meters above sea level in the Himalayan region of Ladakh, and dates to around 1500 years before present (BP). These individuals were genetically homogeneous and had an ancestry signature rare in South Asians today: admixed in roughly 50-50% proportions between a population well-proxied by present-day North Indians, and another genetically similar to ancient Tibetans. By analyzing the typical sizes of segments of DNA inherited from each of these ancestral populations, we find that mixture of these groups began at least fifty generation before the date of the individuals, that is, by around 2800 BP.

Chapter III

Analysis

Comprehensive review of ancestry and genetic findings

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Summary

Key Findings

Ancestry Insights

Traits Analysis

Historical Context

Scientific Assessment