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GWAS Study

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.

Dehghan A, Köttgen A, Yang Q et al.

18834626 PubMed ID
GWAS Study Type
26714 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DA
Dehghan A
KA
Köttgen A
YQ
Yang Q
HS
Hwang SJ
KW
Kao WL
RF
Rivadeneira F
BE
Boerwinkle E
LD
Levy D
HA
Hofman A
AB
Astor BC
BE
Benjamin EJ
VD
van Duijn CM
WJ
Witteman JC
CJ
Coresh J
FC
Fox CS
Chapter II

Abstract

Summary of the research findings

Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel genes associated with serum uric acid concentration and gout.

11,847 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

26714
Total Participants
GWAS
Study Type
Yes
Replicated
11,024 European ancestry individuals, 3,843 African American individuals
Replication Participants
European, African American or Afro-Caribbean
Ancestry
U.S., Netherlands
Recruitment Country
Chapter IV

AI-Generated Summary

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