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GWAS Study

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

Ferreira MA, Matheson MC, Duffy DL et al.

21907864 PubMed ID
GWAS Study Type
57800 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FM
Ferreira MA
MM
Matheson MC
DD
Duffy DL
MG
Marks GB
HJ
Hui J
LS
Le Souëf P
DP
Danoy P
BS
Baltic S
ND
Nyholt DR
JM
Jenkins M
HC
Hayden C
WG
Willemsen G
AW
Ang W
KM
Kuokkanen M
BJ
Beilby J
CF
Cheah F
DG
de Geus EJ
RA
Ramasamy A
VS
Vedantam S
SV
Salomaa V
MP
Madden PA
HA
Heath AC
HJ
Hopper JL
VP
Visscher PM
MB
Musk B
LS
Leeder SR
JM
Jarvelin MR
PC
Pennell C
BD
Boomsma DI
HJ
Hirschhorn JN
WH
Walters H
MN
Martin NG
JA
James A
JG
Jones G
AM
Abramson MJ
RC
Robertson CF
DS
Dharmage SC
BM
Brown MA
MG
Montgomery GW
TP
Thompson PJ
Chapter II

Abstract

Summary of the research findings

We aimed to identify novel genetic variants affecting asthma risk, since these might provide novel insights into molecular mechanisms underlying the disease.

12,475 European ancestry cases, 19,967 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

57800
Total Participants
GWAS
Study Type
Yes
Replicated
3,322 European ancestry cases, 22,036 European ancestry controls
Replication Participants
European
Ancestry
Finland, U.S., Australia, Netherlands
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.